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With early data suggesting that GLP-1 receptor agonists may increase likelihood of pregnancy, we could easily hypothesize higher chances of pregnancies, with resultant bad outcomes for patients on isotretinoin

For instance, combining spironolactone with minoxidil significantly enhances results - improvement rates jump to 65.8% compared to 43.2% with spironolactone alone

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Hellmann J, Zhang MJ, Tang Y, Rane M, Bhatnagar A, Spite M (2013) Increased saturated fatty acids in obesity alter resolution of inflammation in part by stimulating prostaglandin production

Quick Summary: GLP-1 Medications and Inflammation What Are GLP-1 Medications